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| Products > BioPredicta |
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Study of macromolecules and their interaction with ligands has always been a key element in scientific research. BioPredicta equips the researchers to protein preparation, homology modeling, model validation and protein - ligand docking in a seamless fashion. Apart from standard elements of a macromolecule handling software, BioPredicta is equipped with;
- GRIP docking which is an optimal method for accuracy and speed for precision docking
- RAPID docking which is ideal for virtual high throughput screening (vHTS)
- Multiple scoring functions for consensus based molecule profiling
- Single template and multi-template based homology modeling for remote homologue situations
- Comprehensive protein model analysis including Ramchandran plot
BioPredicta is available for both Linux and Windows® operating systems. |
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| VLife Engine: For all molecular operations & key activiies of conformer generation and energy minimization. |
| ProModel: For homology modeling with options for single & multiple template based modeling. |
| VLifeDock: For docking studies with multiple scoring functions & options for Rapid & High Precision modes. |
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| Side chain view of active site residues used to dock ligand into human PBP II protein |
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Algorithms in BioPredicta have wide acceptance in scientific community. These algorithms are either publishes or are patent pending. There are multiple case studies of research conducted with BioPredicta. |
BioPredicta though is an integrated platform for studying & modeling proteins, it has a modular architecture. Customers can buy the whole suite in one-go or buy incrementally to suite their requirement. |
BioPredicta is fully developed in-house with complete ownership of every line of code. This provides unprecedented flexibility to add-on/ customize the product to suite customer specifications as well as integrating it to customers' existing discovery workbench. |
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| VLifeSCOPE:To optimize lead design based on interaction between the molecule and interacting residues in the active site. |
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Application of enzymes to enhance drug action View |
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Target Identification for existing nutraceutical molecule View |
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Homology modeling using BioPredicta View |
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"GRIP docking in BioPredicta is a significant improvement over comparable technologies in terms of accuracy and speed of predictions of docking poses with respect to the co-crystallized X-ray structures."
R. Sowdhamini. Ph.D.
National Centre for Biological Sciences, Tata Institute of Fundamental Research (TIFR) |
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| LeadGrow |
| Combinatorial library generation |
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