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| Products > VLifeMDS |
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VLifeMDS is an integrated platform for Computer Aided Drug Design (CADD) and molecule discovery available for both Windows® and Linux platforms. This integrated suite provides complete toolkit to scientists to perform all scientific functions required to pursue structure based as well as ligand based discovery approaches.
VLifeMDS has a modular architecture perfectly suited for incrementally enhancing the product capability as your discovery projects evolve. It has an intuitive GUI which keeps learning curve very low to enable full utilization almost immediately. |
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| VLifeBase: For molecule draw, visualization and analysis |
| VLife Engine: For all molecular operations and key activity of conformer generation |
| ProModel: For homology modeling with options for manual and automated template based modeling |
| VLifeDock: For docking studies with multiple scoring functions and options for rapid and high precision docking |
| VLifeQSAR: For 2D/ 3D QSAR with multiple variable selection options and regressions methods |
| ChemDBS: For exploring databases with multiple search options including property, fingerprint and pharmacophore based |
| MolSign: For pharmacophore generation and application in optimization and searches |
| LeadGrow: For creating combinatorial library with a choice of substitutions |
| ProViz: For calculating and visualizing molecular properties on the surface of a molecule |
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Peer reviewed algorithms
Algorithms in VLifeMDS have wide acceptance in scientific community. These algorithms are either published or are patent pending. There are multiple case studies of research conducted with VLifeMDS. |
Ease of plug-in/ plug-out
Although an integrated platform, VLifeMDS has a modular architecture. Customers can buy the whole suite in one-go or buy incrementally as per the evolving needs of their research projects. Incremental module additions seamlessly integrate with rest of the modules to provide a consistent experience. |
Ease of customization & integration
VLifeMDS is developed fully in-house with complete ownership of every line of code. This provides unprecedented flexibility to add-on/ customize the product to suit customer specifications as well as integrating it to customers' existing discovery workbench. |
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| GQSAR: To obtain site specific clues for new molecule design and optimization. |
| VLifeSCOPE: To optimize lead design based on interaction between the molecule and interacting residues in the active site. |
| LeadGrow+: An extension to the combinatorial library generation capability that ensures that molecules which can be synthesized can only be generated in a library. |
| Aakar: Shape Based Screening |
| VLife WorkFlow: Customized workflows for research protocols |
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Novel PTP1B inhibitors design using SCOPE method View |
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A novel QSAR technology for new molecule design View |
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A novel regression technique for modeling non-linear activity and property data View |
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"The visualization aspects in VLifeMDS, utilizing superior quality graphics is indeed very useful. I strongly recommend VLifeMDS for any serious research work in the area of in- silico drug design."
Manish C. Bagchi. Ph.D.
Head, Structural Biology and Bioinformatics Division
Indian Institute of Chemical Biology |
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